2021年度以降
2024年04月10日
262. Nair P, Radford K, Nunomura S, Mukherjee M, Izuhara K
Response of sputum periostin to anti-T2 biologics treatment in severe asthma
Allergy, in press
261. Morimoto T, Kobayashi T, Ito H, Tsukamoto M, Yoshihara T, Hirata H, Otani K, Izuhara K, Nunomura S, Mawatari M
Serum periostin levels correlate with severity of intervertebral discdegeneration
European Spine Journal, in press
260. Tajiri T, Suzuki M, Nishiyama H, Ozawa Y, Kurokawa R, Takeda N, Ito K, Fukumitsu K, Kanemitsu Y, Mori Y, Fukuda S, Uemura T, Ohkubo H, Takemura M, Maeno K, Ito Y, Oguri T, Takai M, Izuhara K, Niimi A
Efficacy of dupilumab for airway hypersecretion and airway hyperresponsiveness in moderate-to-severe asthma
Allergology International, in press
259. Kido-Nakahara M, Onozuka D, Izuhara K, Saeki H, Nunomura S, Takenaka M, Matsumoto M, Kataoka Y, Fujimoto R, Kaneko S, Morita E, Tanaka A, Saito R, Okano T, Miyagaki T, Aoki N, Nakajima K, Ichiyama S, Tonomura K, Nakagawa Y, Tamagawa-Mineoka R, Masuda K, Takeichi T, Akiyama M, Ishiuji Y, Katsuta M, Kinoshita Y, Tateishi C, Yamamoto A, Morita A, Matsuda-Hirose H, Hatano Y, Kawasaki H, Nomura A, Ohtsuki M, Kamiya K, Kabata Y, Abe R, Mitsui H, Kawamura T, Tsuji G, Furue M, Katoh N, Nakahara T
Exploring patient background and biomarkers associated with the development of dupilumab-associated conjunctivitis and blepharitis
Allergology International, in press
258. Okamoto M, Fujimoto K, Johkoh T, Kawaguchi A, Mukae H , Sakamoto N, Ogura T, Ikeda S, Kondoh Y, Yamano Y, Komiya K, Umeki K, Nishikiori H, Tanino Y , Tsuda T, Arai N, Komatsu M, Sakamoto S, Yatera K, Inoue Y, Miyazaki Y, Hashimoto S, Shimizu Y, Hozumi H, Ohnishi H, Handa T, Hattori N, Kishaba T, Kato, Inomata M, Ishii H, Hamada N, Konno S, Zaizen Y, Azuma A, Suda T, Izuhara K, Hoshino T
A prospective cohort study of periostin as a serum biomarker in patients with idiopathic pulmonary fibrosis treated with nintedanib
Scientific Reports, 13, 22977, 2023
257. Tateda Y, Suzuki T, Sato T, Izuhara K, Ise K, Shimada H, Murakami K, Murakami K, Nakamura Y, Ohta N
Expression of periostin in benign salivary gland tumors
Tohoku Journal of Experimental Medicine, in press
256. Matama G, Okamoto M, Fujimoto K, Johkoh T, Tominaga M, Mukae H, Sakamoto N, Komiya K, Umeki K, Komatsu M, Shimizu Y, Takahashi K, Tokisawa S, Zaizen Y, Matsuo N, Nouno T, Kaieda S, Ida H, Izuhara K, Hoshino T
Periostin is a biomarker of rheumatoid arthritis-associated interstitial lung disease.
Journal of Clinical Medicine, 12(22), 7100, 2023
255. Suzaki I, Maruyama Y, Kamimura S, Hirano K, Nunomura S, Izuhara K, Kobayashi H
Residual nasal polyp tissue following with dupilumab therapy involves periostin-associated fibrosis
European Archives of Oto-Rhino-Laryngology, in press
254. Nunomura S, Ito R, Nanri Y, Ohno Y, Honda Y, Takedomi H, Izuhara K
Novel mechanisms by which benralizumab suppresses IgE expression in human B cells in humanized mice
Allergy, 78(12), 3271-3273, 2023
253. Tateda Y, Sato T, Ikeda R, Kakuta R, Izuhara K, Ogawa T, Ise K, Shimada H, Katoh M, Murakami K, Murakami K, Nakamura Y, Katori Y, Ohta N
Immunohistochemical localization of CD31, CD34, and periostin in vocal fold polyps
Acta Oto-Laryngologica, 143(9), 806-813, 2023
252. Nakahara Y, Onozuka D, Nunomura S, Saeki H, Takenaka M, Matsumoto M, Kataoka, Y, Fujimoto R, Sakae Kaneko, Morita E, Tanaka A, Saito R, Okano T, Miyagaki T, Aoki N, Nakajima K, Ichiyama S, Kido-Nakahara M, Tonomura K, Nakagawa Y, Tamagawa-Mineoka R, Masuda K, Takeichi T, Akiyama M, Ishiuji Y, Katsuta M, Kinoshita Y, Tateishi C, Yamamoto A, Morita A, Matsuda-Hirose H, Hatano Y, Kawasaki H, Fukushima-Nomura A, Ohtsuki M, Kamiya K, Kabata Y, Abe R, Mitsui H, Kawamura T, Tsuji G, Katoh N, Furue M, Izuhara K
The ability of biomarkers to assess the severity of atopic dermatitis
Journal of Allergy and Clinical Immunology: Global, 3, 100175, 2024
251. Jutel M, Agache I, Zemelka-Wiacek M, Akdis M, Chivato T, Gajdanowicz P, del Giacco S, Gracia IE, Klimek L, Lauerma A, Ollert M, O’Mahony L, Schwarze JKJ, Shamji MH, Skypala I, Palomares O, Pfaar O, Torres MJ, Bernstein JA, Cruz AA, Durham SR, Galli SJ, Gómez RM, Guttmann-Yassky E, Holgate ST, Izuhara K, Kabashima K, Larenas-Linemmann DE, Nadeau KC, Pawankar R, Platts-Mills TAE, Sicherer SH, Park H, Vieths S, Zhang L, Bilò MB, Akdis CA
Nomenclature of allergic diseases and hypersensitivity reactions: adapted to modern needs: An EAACI Position Paper
Allergology, 78(11), 2851-2874, 2023
250. Sasano H, Harada N, Harada S, Takeshige T, Sandhu Y, Tanabe Y, Ishimori A, Matsuno K, Nagaoka T, Ito J, Chiba A, Akiba H, Atsuta R, Izuhara K, Miyake S, Takahashi K
Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmatics
Allergology International, in press
249. Tateda Y, Ikeda R, Kakuta R, Izuhara K, Ogawa T, Ise K, Shimada H, Murakami K, Murakami K, Nakamura Y, Katori Y, Ohta N
Immunohistochemical localization of D-β-aspartic acid and periostin in vocal fold polyps
Tohoku Journal of Experimental Medicine, 260(3), 223-230, 2023
248. Rabe K, Pavord I, Busse W, Chupp G, Izuhara K, Altincatal A, Gall R, Pandit-Abid N, Deniz Y, Rowe P, Jacob-Nara JA, Radwan A
Dupilumab improves long-term outcomes in patients with uncontrolled, moderate-to-severe GINA-based type 2 asthma, irrespective of allergic status
Allergy, 78, 2148-2156, 2023
247. Sandhu Y, Harada N, Sasano H, Harada S, Ueda S, Takeshige T, Tanabe Y, Ishimori A, Matsuno K, Abe S, Nagaoka T, Ito J, Chiba A, Akiba H, Atsuta R, Izuhara K, Miyake S, Takahashi K
Pretreatment frequency of circulating Th17 Cells and FeNO levels predicted the real-world response after 1 Year of benralizumab treatment in patients with severe asthma
Biomolecules, 13, 538, 2023
246. Izuhara K, Fujieda S, Ohta N
The functional role and the clinical application of periostin in chronic rhinosinusitis
Exp Rev Clin Immunol, 19(8), 857-866, 2023
245. Ono J, Takai M, Kamei A, Ohta S, Nair P, Izuhara K, Dahlén SE, James A
A novel assay for improved detection of sputum periostin in patients with asthma
PLOS ONE, 18(2), e0281356,2023
244. Nunomura S, Uta D, Kitajima I, Nanri Y, Matsuda K, Ejiri N, Kitajima M, Ikemitsu H, Koga M, Yamamoto S, Honda Y, Takedomi H, Andoh T, Conway SJ, Izuhara K
Periostin activates distinct modules of inflammation and itching downstream of the type 2 inflammation pathway
Cell Reports, 42(1), 111933, 2023
243. Nanri Y, Nunomura S, Honda Y, Takedomi H, Yamaguchi Y, Izuhara K
A positive loop formed by SOX11 and periostin upregulates TGF-β signals leading to skin fibrosis
Journal of Investigative Dermatology, 143(6), 989-998, 2023
242. Pavord ID, Deniz Y, Corren J, Casale TB, FitzGerald JM, Izuhara K, Daizadeh N, Ortiz B, Johnson RR, Harel S, Djandji M, Goga L, Crikelair N, Rowe P, Busse WW
Baseline FeNO independently predicts the dupilumab response in patients with moderate-to-severe asthma
Journal of Allergy and Clinical Immunology: In Practice, 11(4), 1213-1220.e2, 2023
241. Nakahara T, Izuhara K, Onozuka D, Saeki H, Nunomura S, Takenaka M, Matsumoto M, Kataoka Y, Fujimoto R, Kaneko S, Morita E, Tanaka A, Hide M, Okano T, Miyagaki T, Aoki N, Nakajima K, Ichiyama S, Kido-Nakahara M, Tonomura K, Nakagawa Y, Tamagawa-Mineoka R, Masuda K, Takeichi T, Akiyama M, Ishiuji Y, Katsuta M, Kinoshita Y, Tateishi C, Yamamoto A, Morita A, Matsuda-Hirose H, Hatano Y, Kawasaki H, Tanese K, Ohtsuki M, Kamiya K, Kabata Y, Abe R, Mitsui H, Kawamura, T, Tsuji G, Katoh N, Furue M
Exploring biomarkers to predict clinical improvement of Atopic Dermatitis in patients treated with dupilumab (B-PAD study)
Clinical and Experimental Allergy, 53(2), 233-238, 2023
240. Maruyama A, Tamagawa-Mineoka R, Ueki S, Matsuda K, Yasuda M, Konishi E, Nunomura S, Izuhara K, Arima M, Katoh N
Anaphylaxis associated with eosinophilic sialodochitis via periostin upregulation and mast cell activation
Allergology International, 72(2), 354-356, 2023
239. Okada N, Yazu H, Shimizu E, Fukagawa K, Nunomura S, Saito H, Matsumoto K, Kawaguchi A, Izuhara K, Fujishima H
Biomarkers enable prediction of tacrolimus resistance in patients with severe allergic conjunctivitis
Allergy, 78, 319-321, 2023
238. Tateda Y, Ikeda R, Kakuta R, Ono J, Izuhara K, Ogawa T, Ise K, Shimada H, Murakami K, Murakami K, Nakamura Y, Katori Y, Ohta N
Expression of periostin in vocal fold polyps
Tohoku Journal of Experimental Medicine, 258(1), 5-62, 2022
237. Rabe KF, FitzGerald JM, Bateman ED, Castro M, Pavord ID, Maspero JF, Busse WW, Izuhara K, Daizadeh N, Ortiz B, Pandit-Abid N, Rowe PJ, Deniz Y
Dupilumab is effective in patients with moderate-to-severe uncontrolled GINA-defined type 2 asthma irrespective of an allergic asthma phenotype
Journal of Allergy and Clinical Immunology: In Practice, 10(11), 2916-2924.e4, 2022
236. Takai M, Ono J, Okamoto M, Fujimoto K, Kamei A, Nunomura S, Nanri Y, Ohta S, Hoshino T, Azuma A, Izuhara K
Establishment of a novel ELISA system for measuring periostin independently of formation of the IgA complex
Annals of Clinical Biochemistry, 59, 347-356, 2022
235. Kimura H, Shimizu K, Tanabe N, Makita H, Taniguchi N, Kimura H, Suzuki M, Abe Y, Matsumoto-Sasaki M, Oguma A, Sato M, Takei N, Matsumoto M, Goudarzi H, Sato S, Ono J, Izuhara K, Hirai T, Nishimura M, Konno S.
Further evidence for association of YKL-40 with severe asthma airway remodeling
Annals of Allergy, Asthma & Immunology, 128, 682-688, 2022
234. Yoshida T, Nagaoka T, Nagata Y, Suzuki Y, Tsutsumi T, Kuriyama S, Watanabe J, Togo S, Takahashi F, Matsushita M, Joki Y, Konishi H, Nunomura S, Izuhara K, Conway SJ, Takahashi K.
Periostin-related progression of different types of experimental pulmonary hypertension: A role for M2 macrophage and FGF-2 signaling
Respirology, 27, 529-538, 2022
233. Go H, Ono J, Ohto H, Nollet KE, Sato K, Kume Y, Maeda H, Chishiki M, Haneda K, Ichikawa H, Kashiwabara N, Kanai Y, Ogasawara K, Sato M, Hashimoto K, Nunomura S, Izuhara K, Hosoya M.
In search of biomarkers: Can serum periostin predict bronchopulmonary dysplasia in premature infants?
Pediatric Research, 92(4), 1108-1114, 2022
232. Hirayama J, Fujisawa1 T, Nagao M, Kuwabara Y, Kainuma K, Azuma Y, Ono J, Ohta S, Hirayama M, Izuhara K.
Squamous cell carcinoma antigens (SCCAs) are sensitive biomarkers for atopic dermatitis in children and adolescents: a cross-sectional study.
Asia Pacific Allergy, 11, e42, 2021
231. Nanri Y, Nunomura S, Watanabe T, Ohta S, Yamaguchi Y, Izuhara K.
Expression profile of periostin isoforms in systemic sclerosis.
Journal of Dermatological Science, 104, 210-212, 2021
230. Pfaar O, Blumchen K, Boateng E, Hamelmann E, Iinuma T, Jakob T, Krauss-Etschmann S, Nagase H, Nakajima S, Nakano T, Renz H, Sato S, Taube C, Wagenmann M, Werfel T, Worm M, Izuhara K.
Precision medicine reaching out to the patients in allergology- a German-Japanese workshop report.
Allergologie select, 5, 162-179, 2021.
229. Ono J, Takai M, Kamei A, Azuma Y, Izuhara K.
Pathological roles and clinical usefulness of periostin in type 2 inflammation and pulmonary fibrosis.
Biomolecules, 11, 1084, 2021.
228. Kitaya S, Ohta N, Kitaya S, Yuta A, Ogawa Y, Suzuki Y, Ichihara S, Enomoto T, Kozaki H, Shimizu T, Ono J, Izuhara K, Okamoto Y.
Serum concentrations of antigen-specific IgG4 in patients with Japanese cedar pollinosis.
Allergies, 1, 140-149, 2021.
227. Iwamoto R, Tanoue S, Nagata S, Tabata K, Fukuoka J, Koganemaru M, Sumi A, Chikasue T, Abe T, Murakami D, Takamori S, Ishii H, Ohshima K, Ohta S, Izuhara K, Fujimoto.
T1 invasive lung adenocarcinoma: Thin-section CT solid score and histological periostin expression predict tumor recurrence.
Molecular and Clinical Oncology, 15, 228, 2021.
226. Nunomura S, Kitajima I, Nanri Y, Kitajima M, Ejiri N, Lai IS, Okada N, Izuhara K.
The FADS mouse: A novel mouse model of atopic keratoconjunctivitis.
Journal of Allergy and Clinical Immunology, 148, 1596-1602.E1, 2021.
225. Shimizu H, Sakamoto S, Okamoto M, Isshiki T, Ono J, Shimizu S, Hoshino T, Izuhara K, Homma S.
Association of serum monomeric periostin level with outcomes of acute exacerbation of idiopathic pulmonary fibrosis and fibrosing nonspecific interstitial pneumonia.
Annals of Translational Medicine, 9, 739, 2021.
224. Kurokawa R, Kanemitsu Y, Fukumitsu K, Takeda N, Yap J, Ozawa Y, Masaki A, Ono J, Izuhara K, Nishiyama H, Fukuda S, Uemura T, Tajiri T, Ohkubo H, Maeno K, Ito Y, Oguri T, Takemura M, Suzuki M, Niimi A.
Nasal polyp eosinophilia and FeNO may predict asthma symptoms development after endoscopic sinus surgery in CRS patients without asthma.
Journal of Asthma, 59, 1139-1147, 2022.
223. Nunomura S, Nanri Y, Lefebvre V, Izuhara K.
Epithelial SOX11 regulates eyelid closure during embryonic eye development.
Biochemical and Biophysical Research Communications, 549, 27-33, 2021.
222. Delgado-Eckert E, James A, Meier-Girard D, Kupczyk M, Andersson LI, Bossios A, Mikus M, Ono J, Izuhara K, Middelveld R, Dahlén B, Gaga M, Siafakas NM, Papi A, Beghe B, Joos G, Rabe KF, Sterk PJ, Bel EH, Johnston SL, Chanez P, Gjomarkaj M, Howarth PH, Ni?ankowska-Mogilnicka E, Dahlén S-E, Frey.
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation.
Journal of Allergy and Clinical Immunology, 148, 407-419, 2021.
221. Sunadome H, Matsumoto H, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Iwanaga T, Hozawa S, Niimi A, Kanemitsu Y, Nagasaki T, Tashima N, Ishiyama Y, Morimoto C, Oguma T, Tajiri T, Ito I, Ono J, Ohta S, Izuhara K, Hirai T.
Assessment of serum periostin level as a predictor of requirement for intensive treatment for type-2 inflammation in asthmatics in future: A follow-up study of the KiHAC cohort.
Allergology International, 70, 252-254, 2021.
220. Morimoto C, Matsumoto H, Tajiri T, Gon Y, Ito R, Hashimoto S, Suzukawa M, Ohta K, Izuhara K, Ono J, Ohta S, Ito I, Oguma T, Kanemitsu Y, Nagasaki T, Izuhara Y, Niimi A, Hirai T.
High serum free IL-18 level is associated with decreased omalizumab efficacy: findings from a 2-year omalizumab treatment study.
Journal of Asthma, 58, 1133-1142, 2021.