tel 0952-34-2269
佐賀県佐賀市鍋島5丁目1番1号

2016~2020年度

2023年02月28日

219. Kanemitsu Y, Fukumitsu K, Kurokawa R, Takeda N, Ozawa Y, Masaki A, Ono J, Izuhara K, Yap J, Nishiyama H, Fukuda S, Uemura T, Tajiri T, Ohkubo H, Maeno K, Ito Y, Oguri T, Takemura M, Suzuki M, Niimi A.

Moulds and Staphylococcus aureus enterotoxins are relevant allergens to affect type2 inflammation and clinical outcomes in CRS patients.
ERJ Open Research, 6, 00265-2020, 2020.

218. Nakahara T, Izuhara K, Onozuka D, Nunomura S, Tamagawa-Mineoka R, Masuda K, Ichiyama S, Saeki H, Kabata Y, Abe R, Ohtsuki M, Kamiya K, Okano T, Miyagaki T, Ishiuji Y, Asahina A, Kawasaki H, Tanese K, Mitsui H, Kawamura T, Takeichi T, Akiyama M, Nishida E, Morita A, Tonomura K, Nakagawa Y, Sugawara K, Tateishi C, Kataoka Y, Fujimoto R, Kaneko S, Morita E, Tanaka A, Hide M, Aoki N, Sano S, Matsuda-Hirose H, Hatano Y, Takenaka M, Murota H, Katoh N, Furue.

Biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab (B-PAD study): study protocol.
Medicine, 99, e22043, 2020.

217. Isshiki T, Matsuyama H, Yamaguchi T, Morita T, Ono J, Nunomura S, Izuhara K, Sakamoto S, Homma S, Kishi K.

Plasma matrix metalloproteinase 7, CC-chemokine ligand 18, and periostin as markers for pulmonary sarcoidosis.
Respiratory Investigation, 58, 479-487, 2020.

216. Kanemitsu Y, Kurokawa R, Ono J, Fukumitsu K, Takeda N, Fukuda S, Uemura T, Tajiri T, Ohkubo H, Maeno K, Ito Y, Oguri T, Takemura M, Yap J, Nishiyama H, Masaki A, Ozawa Y, Izuhara K, Suzuki M, Niimi A.

Increased serum periostin levels and eosinophils in nasal polyps are associated with the preventive effect of endoscopic sinus surgery for asthma exacerbations in chronic rhinosinusitis patients.
International Archives of Allergy and Immunology, 181, 862-870, 2020.

215. Tanosaki T, Kabata H, Matsusaka M, Miyata J, Masaki K, Mochimaru T, Okuzumi S, Kuwae M, Watanabe R, Suzuki Y, Sayama K, Izuhara K, Asano K, Fukunaga T.

Clinical characteristics of patients with not well-controlled severe asthma in Japan: analysis of the Keio Severe Asthma Research Program in Japanese Population (KEIO-SARP) registry.
Allergology International, 70, 61-67, 2021.

214. Sunadome H, Matsumoto H, Tachikawa R, Matsumoto T, Tanizawa K, Oga T, Ono J, Ohta S, Izuhara K, Hirai T, ChinT.

Role of serum periostin in severe obstructive sleep apnea with albuminuria.
Respiratory Research, 21, 143, 2020.

213. Asano T, Ohbayashi H, Ariga M, Furuta O, Kudo S, Ono J, Izuhara K.

Serum periostin reflects dynamic hyperinflation in patients with asthma.
ERJ Open Research, 6, 00347-2019, 2020.

212. Hayashi H, Fukutomi Y, Mitsui C, Kajiwara K, Watai K, Kamide Y, Nakamura Y, Hamada Y, Tomita Y, Sekiya K, Tsuburai T, Izuhara K, Wakahara K, Hashimoto N, Hasegawa Y, Taniguchi M.

Omalizumab for aspirin-hypersensitivity and leukotriene overproduction in aspirin- exacerbated respiratory disease: A randomized trial.
American Journal of Respiratory and Critical Care Medicine, 201, 1488-1498, 2020.

211. Matsunaga K, Katoh N, Fujieda S, Izuhara K, Oishi K.

Dupilumab: Basic aspects and applications to allergic diseases.
Allergology International, 69, 187-196, 2020.

210. Tanaka J, Hebisawa A, Oguma T, Tomomatsu K, Suzuki J, Shimizu H, Kawabata Y, Ishiguro T, Takayanagi N, Ueda S, Fukunaga K, Taniguchi M, Ono J, Ohta S, Izuhara K, Asano K.

Evaluating serum periostin levels in allergic bronchopulmonary aspergillosis.
Allergy, 75, 974-977, 2020.

209. Yoshihara T, Nanri Y, Nunomura S, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Mawatari M, Izuhara K.

Periostin plays a critical role in the cell cycle in lung fibroblasts.
Respiratory Research, 21, 38, 2020.

208. Kanemitsu Y, Suzuki M, Fukumitsu K, Asano T, Takeda N, Nakamura Y, Ozawa Y, Masaki A, Ono J, Kurokawa R, Yap J, Nishiyama H, Fukuda S, Ohkubo H, Maeno K, Ito Y, Oguri T, Izuhara K, Takemura M, Niimi A.

A novel pathophysiologic link between upper and lower airways in patients with chronic rhinosinusitis: Association of sputum periostin levels with upper airway inflammation and olfactory function.
World Allergy Organization Journal, 13, 10094, 2020.

207. Oka A, Ninomiya T, Fujiwara T, Takao S, Sato Y, Gion Y, Minoura A, Haruna S, Yoshida N, Sakuma Y, Izuhara K, Ono J, Taniguchi M, Haruna T, Higaki T, Kariya S, Koyama T, Takabayashi T, Imoto Y, Sakashita M, Kidoguchi M, Nishizaki K, Fujieda S, Okano.

Serum IgG4 as a biomarker in chronic rhinosinusitis.
Allergology International, 69, 417-423, 2020

206. Mitamura Y, Nunomura S, Furue M, Izuhara K.

IL-24: A new player in the pathogenesis of proinflammatory and allergic skin diseases.
Allergology International, 69, 405-411,2020.

205. Nanri Y, Nunomura S, Terasaki Y, Yoshihara T, Hirano Y, Yokosaki Y, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Conway SJ, Izuhara K.

The Cross-talk Between TGF-b and periostin can be targeted for pulmonary fibrosis.
American Journal of Respiratory Cell and Molecular Biology ,62, 204-216, 2020.

204. Ono J, Takai M, Kamei A, Nunomura S, Nanri Y, Yoshihara T, Ohta S, Yasuda K, Conway SJ, Yokosaki Y, Izuhara K.

Periostin forms a functional complex with IgA in human.
Allergology International, 69, 111-120, 2020

203. Okamoto M, Izuhara K, Ohta S, Ono J, Hoshino T.

Ability of periostin as a new biomarker of idiopathic pulmonary fibrosis.
Adv Exp Med Biol, 1132, 79-87, 2019

202. Sung M, Baek H, Yeon D, Lee S, Ha E, Lee K, Jee H, Sheen Y, Ono J, Izuhara K, Han M.

Serum periostin level has limited usefulness as a biomarker for allergic disease in 7-year-old children.
International Archives of Allergy and Immunology, 180, 195-201, 2019

201. Izuhara K, Nunomura S, Nanri Y, Ono J, Takai M, Kawaguchi A.

Periostin: An emerging biomarker for allergic diseasest.
Allergy, 74, 2116-2128, 2019

200. Takeuchi S, Furusyo N, Ono J, Azuma Y, Takemura M, Esaki H, Yamamura K, Mitamura Y, Tsuji G, Kiyomatsu-Oda M, Hayashi J, Izuhara K, Furue M.

Serum squamous cell carcinoma antigen (SCCA)-2 correlates with clinical severity of pediatric atopic dermatitis in Ishigaki cohort.
Journal of Dermatological Science, 95, 70-75, 2019

199. Ohta N, Fukase S, Kusano Y, SaitoY, Tateda Y, Ishida Y, Ikeda R, Yamazaki M, Ono J, Izuhara K.

Treatment of auricular hematomas by OK-432: How and why it works.
Otology & Neurotology, 40, e820-e823, 2019

198. Ito R, Maruoka S, Gon Y, Katano I, Takahashi T, Ito M, Izuhara K, Nunomura S.

Recent advances in allergy research using humanized mice.
Int J Mol Sci, 20, E2740, 2019

197. Nukui Y, Miyazaki Y, Masuo M, Okamoto T, Furusawa H, Tateishi T, Kishino M, Tateishi U, Ono J, Ohta S, Izuhara K, Inase N.

Periostin as a predictor of prognosis in chronic bird-related hypersensitivity pneumonitis.
Allergology International, 68, 363-369, 2019

196. Koga Y, Hachisu Y, Tsurumaki H, Yatomi M, Kaira K, Ohta S, Ono J, Izuhara K, Dobashi K, Hisada T.

Pirfenidone Improves Familial Idiopathic Pulmonary Fibrosis without Affecting Serum Periostin Levels.
Medicina, 55, E161, 2019

195. Agache I, Jutel M, Lau S, Akdis CA, Bonini M, Cavkaytar O, Flood B,  Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Papadopoulos N, Smolinska S, Sokolowska M, Angiers E, Fernandes-RM, Halken S, Pajno G, Pfaar O , Roberts G, Ryan D, Sturm G, Ree Rv, Varga EM, Wijk RGv, Dhami S, Sheikh A, Muraro A.

EAACI guidelines on allergen immunotherapy: House dust mite-driven allergic asthma.
Allergy, 74, 855-873, 2019

194. Fujitani H, Kasuga S, Ishihara T, Higa Y, Fujikawa S, Ohta N, Ono J, Izuhara K,  Shintaku H.

Age-related changes in serum periostin level in allergic and non-allergic children.
Allergology International, 68, 285-286, 2019

193. Takahashi K, Meguro K, Kawashima H, Kashiwakuma D, Kagami S, Ohta S, Ono J, Izuhara K, Iwamoto I.

Serum periostin levels serve as a biomarker for both eosinophilic airway inflammation and fixed airflow limitation in well-controlled asthmatics.
Journal of Asthma, 56, 236-243, 2019

192. Cho JH, Kim K, Yoon JW, Choi SH, Sheen YH, Han M, Ono J, Izuhara K, Baek H.
Serum levels of periostin and exercise-induced bronchoconstriction in asthmatic children.
World Allergy Organization Journal, 12, 100004, 2019

191. Nunomura S, Ejiri N, Kitajima M, Nanri Y, Arima K, Mitamura Y, Yoshihara T, Fujii K, Takao K, Imura J, Fehling HJ, Izuhara K, Kitajima I.
Establishment of a Mouse Model of Atopic Dermatitis by Deleting Ikk2 in Dermal Fibroblasts.
J Invest Dermatol, 139, 1274-1283, 2019

190. Mogensen I, Alving K, Dahlen SE, James A, Forsberg B, Ono J, Ohta S, Venge P, Borres MP, Izuhara K, Janson C, Malinovschi A.
Fixed airflow obstruction relates to eosinophil activation in asthmaticsn.
Clin Exp Allergy, 49, 152-162, 2019

189. Ohno F, Nakahara T, Kido-Nakahara M, Ito T, Nunomura S, Izuhara K, Furue M.
Periostin Links Skin Inflammation to Melanoma Progression in Humans and Mice.
Int J Mol Sci, 20, pii: E169, 2019

188. Nakagome K, Nakamura Y, Kobayashi T, Ohta S, Ono J, Kobayashi K, Ikebuchi K, Noguchi T, Soma T, Yamauchi K, Izuhara K, Nagata M.
Elevated Periostin Concentrations in the Bronchoalveolar Lavage Fluid of Patients with Eosinophilic Pneumonia.
Int Arch Allergy Immunol, 178, 264-271, 2019

187. Yasuda M, Harada N, Harada S, Ishimori A, Katsura Y, Itoigawa Y, Matsuno K, Makino F, Ito J, Ono J, Tobino K, Akiba H, Atsuta R, Izuhara K, Takahashi K.
Characterization of tenascin-C as a novel biomarker for asthma: utility of tenascin-C in combination with periostin or immunoglobulin E.
Allergy Asthma Clin Immunol, 14, 72, 2018

186. Lee JH, Kim SH, Choi Y, Trinh HKT, Yang EM, Ban GY, Shin YS, Ye YM, Izuhara K, Park HS.
Serum Periostin Levels: A Potential Serologic Marker for Toluene Diisocyanate-Induced Occupational Asthma.
Yonsei Med J, 59,1214-1221, 2018

185. Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S.
A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis.
JCI Insight, 3, pii: 121580, 2018

184. Yon DK, An J, Ha EK, Jee HM, Izuhara K, Ono J, Jung YH, Lee KS, Sheen YH, Baek H, Han MY.
Serum Periostin Is Negatively Correlated With Exposure to Formaldehyde and Volatile Organic Compounds in Children.
Allergy Asthma Immunol Res, 10, 716-721, 2018

183. Murata K, Koga Y, Kasahara N, Hachisu Y, Nunomura S, Nakajima N, Yokoo H, Kaira K, Maeno T, Dobashi K, Izuhara K, Hisada T.
Accumulation of periostin in acute exacerbation of familial idiopathic pulmonary fibrosis.
J Thorac Dis, 10, E587-E591, 2018

182. Ninomiya T, Noguchi E, Haruna T, Hasegawa M, Yoshida T, Yamashita Y, Okano M, Yoshida N, Haruna S, Sakuma Y, Ohta S, Ono J, Izuhara K, Okada M, Kidoguchi M, Tokunaga T, Okamoto M, Kanno M, Sakashita M, Takabayashi T, Narita N, Fujieda S.
Periostin as a novel biomarker for postoperative recurrence of chronic rhinosinitis with nasal polyps.
Sci Rep, 8, 11450, 2018

181. Mitamura Y, Nunomura S, Nanri Y, Arima K, Yoshihara T, Komiya K, Fukuda S, Takatori H, Nakajima H, Furue M, Izuhara K.
Hierarchical control of interleukin13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11.
J Biol Chem, 293, 14646-14658, 2018

180. Mitamura Y, Nunomura S, Nanri Y, Ogawa M, Yoshihara T, Masuoka M, Tsuji G, Nakahara T, Hashimoto-Hachiya A, Conway SJ, Furue M, Izuhara K.
The IL-13/periostin/IL-24 pathway causes epidermal barrier dysfunction in allergic skin inflammation.
Allergy, 73, 1881-1891, 2018

179. Nagao M, Inagaki S, Kawano T, Azuma Y, Nomura N, Noguchi Y, Ohta S, Kawaguchi A, Odajima H, Ohya Y, Fujisawa T, Izuhara K.
SCCA2 is a reliable biomarker for evaluating pediatric atopic dermatitis.
J Allergy Clin Immunol, 141,1934-1936.e11, 2018

178. Semba T, Sugihara E, Kamoshita N, Ueno S, Fukuda K, Yoshino M, Takao K, Yoshikawa K, Izuhara K, Arima Y, Suzuki M, Saya H.
Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma
Cancer Sci, 109, 1447-1454, 2018

177. Izuhara K, Yamaguchi Y, Ohta S, Nunomura S, Nanri Y, Azuma Y, Nomura N, Noguchi Y, Aihara M.
Squamous Cell Carcinoma Antigen 2 (SCCA2, SERPINB4): An Emerging Biomarker for Skin Inflammatory Diseases.
Int J Mol Sci, 19(4), pii: E1102, 2018

176. Kanaoka M, Yamaguchi Y, Komitsu N, Feghali-Bostwick CA, Ogawa M, Arima K, Izuhara K, Aihara M.
Pro-fibrotic phenotype of human skin fibroblasts induced by periostin via modulating TGF-β signaling
J Dermatol Sci, 90, 199-208, 2018

175. Takahashi K, Meguro K, Kawashima H, Kashiwakuma D, Kagami SI, Ohta S, Ono J, Izuhara K, Iwamoto I.
Serum periostin levels serve as a biomarker for both eosinophilic airway inflammation and fixed airflow limitation in well-controlled asthmatics.
J Asthma, 12, 1-8, 2018

174. Nunomura S, Nanri Y, Ogawa M, Arima K, Mitamura Y, Yoshihara T, Hasuwa H, Conway SJ, Izuhara K.
Constitutive overexpression of periostin delays wound healing in mouse skin.
Wound Repair Regen, 26, 6-15, 2018

173. Kimura H, Konno S, Makita H, Taniguchi N, Kimura H, Goudarzi H, Shimizu K, Suzuki M, Shijubo N, Shigehara K, Ono J, Izuhara K, Ito YM, Nishimura M.
Serum periostin is associated with body mass index and allergic rhinitis in healthy and asthmatic subjects.
Allergology International, 67, 357-363, 2018

172. Matsusaka M, Kabata H, Fukunaga K, Izuhara K, Asano K, Betsuyaku T.
Sub-phenotypes of type 2 severe asthma in adults
J Allergy Clin Immunol: In Practice, 6, 274-276.e2., 2018

171. Okawa T, Yamaguchi Y, Kou K, Ono J, Azuma Y, Komitsu N, Inoue Y, Kohno M, Matsukura S, Kambara T, Ohta S, Izuhara K, Aihara M.
Serum levels of squamous cell carcinoma antigens 1 and 2 reflect disease severity and clinical type of atopic dermatitis in adult patients
Allergology International, 67, 124-130, 2018

170. Izuhara K, Suzuki S, Ogawa M, Nunomura S, Nanri Y, Mitamura Y, Yoshihara T.
The Significance of Hypothiocyanite Production via the Pendrin/DUOX/Peroxidase Pathway in the Pathogenesis of Asthma.
Oxidative Medicine and Cellular Longevity, 1054801,2017.

169. Nakamura H, Akashi K, Watanabe M, Ohta S, Ono J, Azuma Y, Ogasawara N, Yamamoto K, Shimizu N, Tsutsumi H, Izuhara K, Katsunuma T.
Up-regulation of serum periostin and squamous cell carcinoma antigen levels in infants with acute bronchitis due to respiratory syncytial virus.
Allergology International, 67, 259-265, 2018

168. Agache I, Strasser DS, Pierlot GM, Farine H, Izuhara K, Akdis CA.
Monitoring inflammatory heterogeneity with multiple biomarkers for multidimensional endotyping of asthma.
J Allergy Clin Immunol, 141, 442-445, 2018

167. Mino M, Kanno K, Okimoto K, Sugiyama A, Kishikawa N, Kobayashi T, Ono J, Izuhara K, Kobayashi T, Ohigashi T, Ohdan H, Tazuma S.
Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma..
Hepatol Commun, 25, 1099-1109, 2017

166. Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A.
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Allergy, 72, 1825-1848, 2017

165. Asamoah F, Kakourou A, Dhami S, Lau S, Agache I, Muraro A, Roberts G, Akdis C, Bonini M, Cavkaytar O, Flood B, Izuhara K, Jutel M, Kalayci Ö, Pfaar O, Sheikh A.
Allergen immunotherapy for allergic asthma: a systematic overview of systematic reviews
Clin Transl Allergy, 7, 25, 2017

164. Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T,
Characteristics of severe asthma with fungal sensitization
Ann Allergy Asthma Immunol, 119, 253-257, 2017

163. Izuhara K, Nunomura S, Nanri Y, Ogawa M, Ono J, Mitamura Y, Yoshihara T,
Periostin in inflammation and allergy
Cell Mol Life Sci, 74, 4293-4303, 2017

162. James A, Janson C, Malinovschi A, Holweg C, Alving K, Ono J, Ohta S, Ek A, Middelveld R, Dahlén B, Forsberg B, Izuhara K, Dahlén S-E,
Serum periostin relates to type-2 inflammation and lung function in asthma; data from the large population-based cohort Swedish GA(2)LEN
Allergy, 72, 1753-1760, 2017

161. Sunadome H, Matsumoto H, Petrova G, Kanemitsu,Y, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Nagasaki T, Ito Isao, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Hirota T, Tamari M, Yokoyama T, Niimi A, Izuhara K, Mishima M,
IL4Rα and ADAM33 as genetic markers in asthma exacerbations and type-2 inflammatory endotype
Clin Exp Allergy, 47, 998-1006, 2017

160. Ishihara S, Shoda T, Ishimura N, Ohta S, Ono J, Azuma Y, Okimoto E, Izuhara K, Nomura I, Matsumoto K, Kinoshita Y,
Serum biomarkers for diagnosis of eosinophilic esophagitis and eosinophilic gastroenteritis
Intern Med, 56, 2819-2825, 2017

159. Nakama T, Yoshida S, Ishikawa K, Kubo Y, Kobayashi Y, Zhou Y, Nakao S, Hisatomi T, Ikeda Y, Takao K, Yoshikawa K, Matsuda A, Ono J, Ohta S, Izuhara K, Kudo A, Sonoda KH, Ishibashi T,
Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization
Mol Ther Nucleic Acids, 6, 279-289, 2017

158. Nagasaki T, Matsumoto H, Izuhara K, and the KiHAC Respiratory Medicine Group,
Utility of serum periostin in combination with exhaled nitric oxide in the management of asthma
Allergology International, 66, 404-410, 2017

157. Asano T, Kanemitsu Y, Takemura M, Yokota M, Fukumitsu K, Takeda N, Ichikawa H, Uemura T, Takakuwa O, Ohkubo H, Maeno K, Ito Y, Oguri T, Maki Y, Ono J, Ohta S, Nakamura Y, Izuhara K, Suzuki M, Niimi A,
Serum periostin as a biomarker for comorbid chronic rhinosinusitis in patients with asthma
Annals ATS, 14, 667-675, 2017

156. Ohta S, Okamoto M, Fujimoto K, Sakamoto N, Takahashi K, Yamamoto H, Kushima H, Ishii H, Akasaka K, Ono J, Kamei A, Azuma Y, Matsumoto H, Yamaguchi Y, Aihara M, Johkoh T, Kawaguchi A, Ichiki M, Sagara H, Kadota J, Hanaoka M, Hayashi S, Kohno S, Hoshino T, Izuhara K,
The usefulness of monomeric periostin as a biomarker for idiopathic pulmonary fibrosis
PLOS ONE, 12, e0174547, 2017

155. Komiya K, Ohta S, Arima K, Ogawa M, Suzuki S, Mitamura Y, Nunomura S, Nanri Y, Yoshihara T, Kagwaguchi A, Kadota J, Bruce K. Rubin, Izuhara K,
Clarithromycin attenuates IL-13?induced periostin production in human lung fibroblasts
Respir Res, 18, 37, 2017

154. Kimura H, Konno S, Nakamaru Y, Makita H, Taniguchi N, Shimizu K, Suzuki M, Ono J, Izuhara K, Nishimura M,
Sinus computed tomographic findings in adult smokers and nonsmokers with asthma. analysis of clinical indices and biomarkers
Annals ATS, 14, 332-341, 2017

153. Matsumoto H, Kanemitsu Y, Nagasaki T, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Izuhara Y, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Ono J, Ohta S, Hirota T, Kawaguchi T, Tamari M, Yokoyama T, Tabara Y, Matsuda F, IIzuhara K, Niimi A, Mishima M,
Staphylococcus aureus enterotoxin sensitization involvement and its association  with CysLTR1 variant in different asthma phenotypes
Annals of Allergy, Asthma & Immunology118, 197-203, 2017

152. Ishimori A, Harada N, Chiba A, Harada S, Matsuno K, Makino F, Ito J, Ohta S, Ono J, Atsuta R, Izuhara K, Takahashi K, Miyake S
Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma
Allergology International66, 302-309, 2017

151.Thuwajit C, Thuwajit P, Jamjantra P, Pairojkul C, Wongkham S, Bhudhisawasdi V, Ono J, Ohta S, Fujimoto K, Izuhara K
Clustering of intrahepatic cholangiocarcinoma patients based on serum periostin can predict its prognosis
Oncology Letters14, 623-634, 2017

150. Suzaki I, Kawano S, Komiya K, Tanabe T, Akaba T, Asano K, Suzaki H, Izuhara K, Rubin BK
IL-13 induces periostin production in airway epithelial cells, and inhibiting periostin attenuates IL-13-induced MUC5AC protein expression
Respirology22, 93-100, 2017

149. Sugiyama A, Kanno K, Nishimichi N, Ohta S, Ono J, Conway SJ, Izuhara K, Yokosaki Y, Tazuma S
Periostin promotes hepatic fibrosis in mice by modulating hepatic stellate cell activation via αv integrin interaction
Journal of Gastroenterology51, 1161–1174, 2016

148. Suzuki S, Ogawa M, Ohta S, Arima K, Nunomura S, Nanri Y, Mitamura Y, Yoshihara T, Nakamura Y, Yamauchi K, Chibana K, Ishii Y, Lee JJ, Aratani Y, Kakuta S, Kubo S, Iwakura Y, Yoshida H, Izuhara K
The potential for repositioning anti-thyroid agents as anti-asthma drugs
J Allergy Clin Immunol, 138, 1458-1461, 2016

147. Kim M, Yoon MK, Lee Y-S, Izuhara K, Ohta S, Ono J, Kim J-H, Ban GY, Ye Y-M, Park H-S
Clinical implication of the serum periostin level for differentiating phenotypes of NSAID hypersensitivity
Allergology International, 65, 492-494, 2016

146.Tajiri T, Matsumoto H, Gon Y, Ito R, Hashimoto S, Izuhara K, Suzukawa M, Ohta K, Ono J, Ito I, Oguma T, Inoue H, Iwata T, Nagasaki T, Kanemitsu T, Niimi A, Mishima M
Serum periostin and free IgE levels in the responsiveness to omalizumab in patients with severe asthma
Allergy71, 1472–1479, 2016

145. Inoue T, Akashi K, Watanabe M, Ikeda Y, Ashizuka S, Motoki T, Suzuki R, Sagara N, Yanagida N, Sato S, Ebisawa M, Ohta S, Ono J, Izuhara K, Katunuma T
Periostin as a biomarker for diagnosis of pediatric asthma
Pediatric Allergy and Immunology27, 521-526, 2016

144. Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A
Allergen immunotherapy for allergic asthma: protocol for a systematic review
Clinical and Translational Allergy6, 5, 2016

143. Izuhara K, Ohta S, Ono S
Using periostin as a biomarker in the treatment of asthma
Allergy, Asthma and Immunology Research8, 491-498, 2016

142. Fujishima H, Okada N, Matsumoto K, Fukagawa K, Igarashi A, Matsuda A, Ono J, Ohta S, Mukai H, Yoshikawa M, Izuhara K
The usefulness of measuring tear periostin for the diagnosis and management of ocular allergic diseases
Journal of Allergy and Clinical Immunology138, 459-467, 2016

141. Hinks T, Brown T, Lau LCK, Rupani H, Barber C, Elliott S, Ward JA, Ono J, Ohta S, Izuhara K, Djukanovi? R, Kurukulaaratchy R, Chauhan A, Howarth PH
Multidimensional endotyping in severe asthma reveals inflammatory heterogeneity in MMPs and YKL-40
Journal of Allergy and Clinical Immunology138, 61-75, 2016

140. Bae Y, Izuhara K, Ohta S, Ono J, Hong GU, Ro JY, Park GH, Choi JH.
Periostin and Interleukin-13 Are Independently Related to Chronic Spontaneous Urticaria
Allergy, Asthma & Immunology Research8, 457-460, 2016

139. Watanabe Y, Yamaguchi Y, Komitsu N, Ohta S, Azuma Y, Izuhara K, Aihara M
Elevation of serum squamous cell carcinoma antigen 2 in patients with psoriasis: associations with disease severity and response to the treatment
British Journal of Dermatology174, 1327-1336, 2016

138. Izuhara K, Conway SJ, Moore BB, Matsumoto H, Holweg CTJ, Matthews JG, Arron JR
Roles of periostin in respiratory disorders
American Journal of Respiratory and Critical Care Medicine193, 949-956, 2016

137. James AJ, Reinius LE, Verhoek M, Gomes A, Kupczyk M, Hammar U, Ono J, Ohta S, Izuhara K, Bel E, Kere J, Söderhäll C, Dahlén B, Boot RG, Dahlén S
Increased YKL-40 and chitotriosidase in asthma and chronic obstructive pulmonary disease
American Journal of Respiratory and Critical Care Medicine193, 131-142, 2016

136.Tachibana T, Yoshida S, Kobayashi Y, Nakama T, Ishikawa K, Nakao S, Izuhara K, Kono T, Ishibashi T
Reduced vitreal concentration of periostin after vitrectomy in patients with proliferative diabetic retinopathy
Acta Ophthalmologica94, e81-e82, 2016