tel 0952-34-2269
佐賀県佐賀市鍋島5丁目1番1号

2006〜2010年度

2023年02月27日

89. Matsushita M, Ohta S, Shiraishi H, Suzuki S, Arima K, Toda S, Tanaka H, Nagai H, Kimoto M, Inokuchi A, Izuhara K:
Endotoxin tolerance attenuates airway allergic inflammation in model mice by suppression of the T-cell stimulatory effect of dendritic cells
International Immunology22, 739-747, 2010

88. Suzuki K, Inokuchi A, Miyazaki J, Kuratomi Y, Izuhara K:
Relationship between squamous cell carcinoma-related antigen and the clinical severity in allergic rhinitis patients caused by D. farinae and Japanese cedar pollen
Annals of Otology, Rhinology & Laryngology119, 22-26, 2010

87. Ito T, Suzuki S, Kanaji S, Shiraishi H, Ohta S, Arima K, Tanaka G, Tamada T, Honjo E, Garcia KC, Kuroki R, Izuhara K:
Distinct structural requirements for IL-4 and IL-13 binding to the shared IL-13 receptor facilitate cellular tuning of cytokine responsiveness.
Journal of Biological Chemistry284, 24289-24296, 2009

86. Izuhara K, Ohta S, Shiraishi H, Suzuki S, Taniguchi K, Toda S, Tanabe T, Yasuo M, Kubo K, Hoshino T, Aizawa H:
The mechanism of mucus production in bronchial asthma.
Current Medicinal Chemistry16, 2867-2875, 2009

85. Kanaji S, Kanaji T, Honda M, Nakazato S, Wakayama K, Tabata Y, Shibata S, Gondo H, Nakamura I, Node K, Miura M, Miyahara M, Okamura T, Nagumo F, Ohta S, Izuhara K: Identification of four novel mutations in F5 associated with congenital factor V deficiency.
International Journal of Hematology89, 71-75, 2009

84. Ohta S,Azuma Y,Shiraishi H,Noguchi Y,Izuhara K:
Establishment of the diagnostic system for allergic diseases aiming the
personalized medicine -Establishment of a novel ELISA system for SCCA-
Rinsho Byori56, 980-985, 2008 (Japanese)

83. 86 Sonoda E, Aoki S, Uchihashi K, Soejima H, Kanaji S, Izuhara K, Satoh S, Fujitani N, Sugihara H, Toda S: A new organotypic culture of adipose tissue fragments maintains viable mature adipocytes for a long term, together with development of immature adipocytes and mesenchymal stem cell-like cells. Endocrinology, 149, 4794-4798, 2008

82. Izuhara K, Ohta S, Kanaji S, Shiraishi H, Arima K:
Recent progress in understanding the diversity of the human ov-serpin/clade B serpin family.
Cellular and Molecular Life Sciences65, 2541-2553, 2008

81.Oku E, Kanaji T, Takata Y, Oshima K, Seki R, Morishige S, Imamura R, Ohtsubo K, Hashiguchi M, Osaki K, Yakushiji K, Yoshimoto K, Ogata H, Hamada H, Izuhara K, Sata M, Okamura T: Periostin and bone marrow fibrosis
International Journal of Hematology88, 57-63, 2008

80. Honjo E, Shoyama Y, Tamada T, Shigematsu H, Hatanaka T, Kanaji S, Arima K, Ito Y, Izuhara K, Kuroki R. Expression of the extracellular region of the human interleukin-4 receptor ? chain and interleukin-13 receptor ?1 chain by a silkworm-baculovirus system.
Protein Expression and Purification60, 25-30, 2008

79. Nakao I, Kanaji S, Ohta S, Matsushita H, Arima K, Yuyama N, Yamaya M, Nakayama K, Kubo H, Watanabe M, Sagara H, Sugiyama K, Tanaka H, Toda S, Hayashi H, Inoue H, Hoshino T, Nakajima A, Inoue M, Suzuki K, Aizawa H, Okinami S, Nagai H, Hasegawa M, Fukuda T, Green ED, Izuhara K: Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease.
Journal of Immunology
180, 6262-6269, 2008

78. Izuhara K, Kanaji S, Arima K, Ohta S, Shiraishi H: Involvement of cysteine protease inhibitors in the defense mechanism against parasites
Medicinal Chemistry, 4, 322-327, 2008

77. Kanaji S, Kanaji T, Migita M, Kunishima S, Kunicki TJ, Okamura T, Izuhara K: Characterization of a patient with atypical amegakaryocytic thrombocytopenia. European Journal of Haematology, 80, 361-364, 2008

76. Ohkuri T, Takeda C, Yoshida Y, Izuhara K, Imoto T, Ueda T: Expression of human IL-13 receptor ?2 extracellular domain in Pichia pastoris. Protein Expression and Purification, 56, 48-53, 2007

75. Kanaji S, Tanaka Y, Sakata Y, Takeshita K, Arima K, Ohta S, Hansell EJ, Caffrey C, Mottram JC, Lowther J, Donnelly S, Stack C, Kadowaki T, Yamamoto K, McKerrow JH, Dalton JP, Coombs GH, Izuhara K:
Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases
FEBS Letters581, 4260-4264, 2007

74. Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T, Nakanishi K:
T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-g and IL-13 production     
Proceedings of the National Academy of Sciences of the United States of America104, 14765-14770, 2007

73. Andrews A-L, Buccheri F, Arima K, Izuhara K, Holgate ST, Davies DE Holloway JW:
Effect of IL-13Ra2 Receptor levels on the biological activity of IL-13 variant R110Q
Journal of Allergy and Clinical Immunology120, 91-97, 2007

72. Yoshida Y, Ohkuri T, Takeda C, Kuroki R, Izuhara K, Imoto T, Ueda T:
Analysis of internal motions of interleukin 13 variant associated with severe bronchial asthma using 15N NMR relaxation
Biochemical and Biophysical Research Communications358, 292-297, 2007

71. Izuhara K, Arima K, Kanaji S, Kanaji T, Ohta S:
IL-13 and its signal pathway: promising targets in the development of a therapeutic agent for bronchial asthma
Current Signal Transduction Therapy, 2, 31-40, 2007

70. Izuhara K, Saito H:
Microarray-based identification of novel biomarkers in asthma
Allergology International, 4: 361-367, 2006

69. Izuhara K, Arima K, Kanaji S, Ohta S, Kanaji T:
IL-13: A promising therapeutic target for bronchial asthma
Current Medicinal Chemistry, 13, 2291-2298, 2006

68. Takayama G, Arima K, Kanaji T, Toda S, Tanaka H, Shoji S, McKenzie AN J, Nagai H, Hotokebuchi T, Izuhara K:
Periostin: A novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
Journal of Allergy and Clinical Immunology, 118: 98-104, 2006

67. Koike E, Toda S, Yokoi F, Izuhara K, Koike N, Itoh K, Miyazaki K, Sugihara H:
Expression of new human inorganic pyrophosphatase in thyroid diseases: Its intimate association with hyperthyroidism
Biochemical and Biophysical Research Communications, 341, 691-696, 2006

66. Goda C, Kanaji T, Kanaji S, Tanaka G, Arima K, Ohno S, Izuhara K:
Involvement of IL-32 in activation-induced cell death in T cells
International Immunology, 18, 233-240, 2006