九州大学臨床分子医学講座時代
2023年02月27日
38. Ikizawa K, Kajiwara K, Izuhara K, Yanagihara Y:
PKCd and z mediate IL-4/IL-13-induced germline e transcription in human B cells: a putative regulation via PU.1 phosphorylation
Biochemical and Biophysical Research Communications, 288: 34-41, 2001
37. Ohshima K, Akaiwa M, Umeshita R, Suzumiya J, Izuhara K, Kikuchi M:
Interleukin-13 and interleukin-13 receptor in Hodgkin’s disease: possible autocrine mechanism and involvement in fibrosis
Histopathology, 38: 368-375, 2001
36. Akaiwa M, Yu B, Umeshita R, Terada N, Suto H, Koga T, Arima K, Matsushita S, Saito H, Ogawa H, Furue M, Hamasaki N, Ohshima K, Izuhara K:
Localization of human interleukin-13 receptor in non-hematopoietic cells
Cytokine, 13: 75-84, 2001
35. Izuhara K, Yanagihara Y, Hamasaki N, Shirakawa T, Hopkin, JM:
Atopy and the human Interleukin-4 Receptor a Chain
Journal of Allergy and Clinical Immunology, 106, S65-S71, 2000
34. Umeshita-Suyama, R., Sugimoto, R., Akaiwa, M., Arima, K., Yu, B., Wada, M., Kuwano, M., Nakajima, K., Hamasaki, N., and Izuhara, K.
Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation. International Immunology 12: 1499-1509 (2000).
33. Izuhara K, Umeshita-Suyama R, Akaiwa M, Shirakawa T, Deichmann KA, Arima K, Hamasaki N, Hopkin JM:
Recent advances in understanding how interleukin-13 signals are involved in the pathogenesis of bronchial asthma
Archivum Immunologiae et Therapiae Experimentalis, 48: 505-512, 2000
32. Takabayashi A, Ihara K, Sasaki Y, Suzuki Y, Nishima S, Izuhara K, Hamasaki N, Hara T:
Positive association with a polymorphism of interleukin-4 receptor a gene but not with that of interleukin-4 promoter or Fce receptor 1 b gene
Experimental and Clinical Immunogenetics, 17: 63-70, 2000
31. Arinobu Y, Sugimoto R, Akaiwa M, Arima K, Otsuka T, Hamasaki N, Izuhara K:
Augmentation of signal transducer and activation of transcription (STAT)6 and STAT3 expression in stimulated B and T cells
Biochemical and Biophysical Research Communications, 277: 317-324, 2000
30. Gao P-S, Mao X-Q, Roberts MH, Arinobu Y, Akaiwa M, Enomoto T, Dake Y, Kawai M, Sasaki S, Hamasaki N, Izuhara K, Shirakawa T, Hopkin JM:
Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma
Journal of Medical Genetics, 37: 380-382, 2000
29. Kojima M, Morisaki T, Izuhara K, Uchiyama A, Matsunari M, Katano M, Tanaka M:
Lipopolysaccharide increases cyclo-oxygenase-2 production in a colon carcinoma cell line through nuclear factor-kB activation
Oncogene, 19: 1225-1231, 2000
28. Heinzmann A, Mao X-Q, Akaiwa M, Kreomer RT, Gao P-S, Ohshima K, Umeshita R, Abe Y, Braun S, Yamashita T, Roberts MH, Sugimoto R, Arima K, Arinobu Y, Yu B, Kruse S, Enomoto T, Dake Y, Kawai M, Shimazu S, Sasaki S, Adra CN, Kitaichi M, Inoue H, Yamauchi K, Tomichi N, Kurimoto F, Hamasaki N, Hopkin JM, Izuhara K, Shirakawa T, Deichmann KA:
Genetic variants of IL-13 signalling and human asthma and atopy
Human Molecular Genetics, 9: 549-559, 2000
27. Shirakawa T, Deichman KA, Izuhara K, Mao X-Q, Adra CN, Hopkin JM:
Atopy and asthma: genetic variants of IL-4 and IL-13 signalling
Trends in Immunology (formerly Immunology Today), 21: 60-64, 2000
26. Nemoto Y, Otsuka T, Niiro K, Izuhara K, Yamaoka H, Nakashima H, Niho Y:
Differential effects of interleukin-4 and interleukin-10 on nitric oxide production by murine macrophages
Inflammation Research, 48: 643-650, 1999
25. Izuhara K, Shirakawa T, Adra CN, Hamasaki N, Hopkin JM:
Emerging therapeutic targets in allergy: IL-4Ra and Stat6
Emerging Therapeutic Targets, 3: 381-389, 1999
24. Yamaoka K, OtsukaT, Niiro N, Nakashima H, Tanaka Y, Nagano S, Ogami E, Niho Y, Hamasaki N, Izuhara K:
Selective DNA-binding activity of interleukin-10-stimulated STAT molecules in human monocytes
Journal of Interferon & Cytokine Research, 19: 679-685, 1999
23. Akaiwa M, Yae Y, Sugimoto R, Suzuki SO, Iwaki T, Izuhara K, Hamasaki N:
Hakata Antigen, a new member of the Ficolin/Opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bile
Journal of Histochemistry & Cytochemistry, 47: 777-785, 1999
22. Izuhara K, Arinobu Y, Sumimoto H, Nunoi N, Takeya R, Higuchi K, Takeshige K, Hamasaki N, Harada N:
Association of the interleukin-4 receptor a chain with p47phox, an activator of the phagocyte NADPH oxidase in B cells
Molecular Immunology, 36: 45-52, 1999
21. Arinobu Y, Atamas SP, Otsuka T, Niiro H, Yamaoka K, Mitsuyasu H, Niho Y, Hamasaki N, White B, Izuhara K:
Antagonistic effects of an alternative splice variant of human IL-4, IL-4d2, on IL-4 activities in human monocytes and B cells
Cellular Immunology, 191: 161-167, 1999
20. Mitsuyasu H, Yanagihara Y, Mao X-Q, Gao P-S, Arinobu Y, Ihara K, Takabayashi A, Hara T, Enomoto T, Sasaki S, Kawai M, Hamasaki N, Shirakawa T, Hopkin JM, Izuhara K:
Dominant effect of Ile50Val variant of the human interleukin-4 receptor a chain in IgE synthesis
Journal of Immunology, 162: 1227-1231, 1999
19. Kanai N, Yanai F, Hirose S, Nibu K, Izuhara K, Tani T, Kubota T, Mitsudome A:
A “G” to “A” transition at the last nucleotide mutation of exon 6 of the gc gene (868G→A) may result in either a splice or missense mutation in patients with X-linked severe combined immunodeficiency
Human Genetics, 104: 36-42, 1999
18. Izuhara K, Shirakawa T:
The Signal transduction via the interleukin-4 receptor and its correlation with atopy
International Journal of Molecular Medicine, 3: 3-10, 1999
17. Niiro H, Otsuka T, Ogami E, Yamaoka K, Nagano S, Akahoshi M, Nakashima H, Arinobu Y, Izuhara K, Niho Y:
MAP kinase pathways as a route for regulatory mechanisms of IL-10 and IL-4 which inhibit COX-2 expression in human monocytes
Biochemical and Biophysical Research Communications, 250: 200-205, 1998
16. Sugimoto R, Yae Y, Akaiwa M, Kitajima S, Shibata Y, Sato H, Hirata J, Okochi K, Izuhara K, Hamasaki N:
Cloning and characterization of Hakata Antigen, a member of the Ficolin/Opsonin p35 lectin family
Journal of Biological Chemistry, 273: 20721-20727, 1998
15. Harada N, Higuchi K, Wakao H, Hamasaki N, Izuhara K:
Identification of the critical portions of the human IL-4 receptor a chain of activation of STAT6
Biochemical and Biophysical Research Communications, 246: 675-680, 1998
14. Mitsuyasu M, Izuhara K, Mao X-Q, Arinobu Y, Enomoto T, Kawai M, Sasaki S, Gao P-S, Dake Y, Hamasaki N, Shirakawa T, Hopkin JM:
Ile50Val variant of IL4Ra upregulates IgE synthesis and associates with atopic asthma
Nature Genetics, 19: 119-120, 1998
13. Murakami Y, Nakano S, Niho Y, Hamasaki N, Izuhara K:
Constitutive activation of Jak-2 and Tyk-2 in a v-Src-transformed human gallbladder adenocarcinoma cell line
Journal of Cellular Physiology, 175: 220-228, 1998
12. Yamaoka K, Otsuka T, Niiro H, Arinobu Y, Niho Y, Hamasaki N, Izuhara K:
Activation of STAT5 by lipopolysaccharide through granulocyte-macrophage colony-stimulating factor production in human monocytes
Journal of Immunology, 160: 838-845, 1998