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| 日時 | 担当者 | 紹介論文（中心論文あるいは最新論文のみ） |
| 2003年11月25日 | 金地（佐） | |
| 12月1日 | 坂田 | Tsujimoto Y. J Cell Physiol 195: 158-167, 2003 |
| 8日 | 王 | |
| 15日 | 城 | Hoopengardner B et al. Science 301: 832-836, 2003 |
| 22日 | 合田 | Omori M et al. Immunity 19: 281-294, 2003 |
| 2004年1月13日 | 東元 | Mitsui K et al. Cell 113: 631-642, 2003 |
| 19日 | 高山 | Calvi LM et al. Nature 425: 841-846, 2003 |
| 26日 | 八木 | Wedekind JE et al. Trend Genet 19: 207-216, 2003 |
| 2月2日 | 木本 | He YW et al. The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol 5: 88-97, 2004 |
| 9日 | 中尾 | Herrera E et al. Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell 114: 545-557, 2003 |
| 16日 | 矢ケ部 | Liu G et al. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet 36(1): 63-68, 2004 |
| 23日 | 福留 | Sato N et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 10(1) : 55 - 63, 2004 |
| 3月1日 | 金地（泰） | Paw BH et al. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet 34: 59-64, 2003 |
| 8日 | 伊藤 | J Biol Chem 278: 1101-1107, 2003 |
| 15日 | 趙衛 | Martinowich K et al. DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation. Science 302: 890-893, 2003 |
| 22日 | 有馬 | Chen Q et al. Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress. Immunity 20: 59-70, 2004 |
| 29日 | 張 | Lin SY et al. Multiple Tumor Suppressor Pathways Negatively Regulate Telomerase. Cell 113: 881-889, 2003 |
| 4月5日 | 常吉 |
Aluvihare VR, Kallikourdis M, Betz AG. "Regulatory T cells mediate maternal tolerance to the fetus." Nat Immunol. 2004;5(3):266-71. [Pubmed] |
| 12日 | 高崎 |
Hohsaka T, Muranaka N, Komiyama C, Matsui K, Takaura S, Abe R, Murakami H, Sisido M. "Position-specific incorporation of dansylated non-natural amino acids into streptavidin by using a four-base codon." FEBS Lett. 2004;560(1-3):173-7. [Pubmed] |
| 19日 | 岡本 |
Ooe N, Saito K, Mikami N, Nakatuka I, Kaneko H. "Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression." Mol Cell Biol. 2004;24(2):608-16. [Pubmed] |
| 26日 | 出原 |
Matsumoto A, Comatas KE, Liu L, Stamler JS. "Screening for nitric oxide-dependent protein-protein interactions." Science 2003;301(5633):657-61. [Pubmed] |
| 5月3日 | 休み | Constitution Memorial Day of Japan |
| 10日 | 安藤 |
Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, Ward CM, Crawford TO, Gotow T, Uchiyama Y, Ellisman MH, Calcutt NA, Cleveland DW. "NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth." J Cell Biol. 2003;163(5):1011-20. [Pubmed] |
| 17日 | 太田 |
Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K, Saya H. "Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells." Cell 2003;114(5):585-98. [Pubmed] |
| 24日 | 田中剛 |
Ozaki K, Inoue K, Sato H, Iida A, Ohnishi Y, Sekine A, Sato H, Odashiro K, Nobuyoshi M, Hori M, Nakamura Y, Tanaka T. "Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro." Nature 2004;429(6987):72-5. [Pubmed] |
| 31日 | 富枡 |
Casola S, Otipoby KL, Alimzhanov M, Humme S, Uyttersprot N, Kutok JL, Carroll MC, Rajewsky K. "B cell receptor signal strength determines B cell fate." Nat Immunol. 2004;5(3):317-27. [Pubmed] |
| 6月7日 | 檜垣 |
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferr? P, Birnbaum MJ, Stuck BJ, Kahn BB. "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." Nature 2004;428(6982):569-74. [Pubmed] |
| 14日 | 坂田 |
He W, Miao FJ, Lin DC, Schwandner RT, Wang Z, Gao J, Chen JL, Tian H, Ling L. "Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors." Nature 2004;429(6988):188-93. [Pubmed] |
| 21日 | 副島 |
Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T. "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells." Cell 2003;115(1):109-21. [Pubmed] |
| 28日 | 金地（佐） |
Kawaguchi Y, Kovacs JJ, McLaurin A, Vance JM, Ito A, Yao TP. "The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress." Cell 2003;115(6):727-38. [Pubmed] |
| 7月5日 | 増本 |
Azzouz M, Ralph GS, Storkebaum E, Walmsley LE, Mitrophanous KA, Kingsman SM, Carmeliet P, Mazarakis ND. "VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model." Nature 2004;429(6990):413-7. [Pubmed] |
| 12日 | 城 |
Martens JA, Laprade L, Winston F. "Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene." Nature 2004;429(6991):571-4. [Pubmed] |
| 20日 | 東元 |
Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH. "A small modulatory dsRNA specifies the fate of adult neural stem cells." Cell 2004;116(6):779-93. [Pubmed] |
| 26日 | 高山 |
Abe E, Marians RC, Yu W, Wu XB, Ando T, Li Y, Iqbal J, Eldeiry L, Rajendren G, Blair HC, Davies TF, Zaidi M. "TSH is a negative regulator of skeletal remodeling." Cell 2003;115(2):151-62. [Pubmed] |
| 8月いっぱい | 夏休み | |
| 9月6日 | 八木 |
Kino Y, Mori D, Oma Y, Takeshita Y, Sasagawa N, Ishiura S. "Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats." Hum Mol Genet. 2004;13(5):495-507. [Pubmed] |
| 13日 | 吉田 |
Amsen D, Blander JM, Lee GR, Tanigaki K, Honjo T, Flavell RA. "Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells." Cell 2004;117(4):515-26. [Pubmed] |
| 21日 | 木本 |
Pancer Z, Amemiya CT, Ehrhardt GR, Ceitlin J, Gartland GL, Cooper MD. "Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey." Nature 2004;430(6996):174-80. [Pubmed] |
| 27日 | 中尾 |
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. "Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase." Science 2004;305(5682):390-2. [Pubmed] |
| 10月4日 | 矢ケ部 |
Morris JR, Solomon E. "BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair." Hum Mol Genet. 2004;13(8):807-17. [Pubmed] |
| 12日 | 福留 |
Maldonado RA, Irvine DJ, Schreiber R, Glimcher LH. "A role for the immunological synapse in lineage commitment of CD4 lymphocytes." Nature 2004;431(7008):527-32. [Pubmed] |
| 18日 | 金地（泰） |
Oikawa T, Yamaguchi H, Itoh T, Kato M, Ijuin T, Yamazaki D, Suetsugu S, Takenawa T. "PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia." Nat Cell Biol. 2004;6(5):420-6. [Pubmed] |
| 25日 | 趙衛 | Nature 431, 211 - 217 (09 September 2004) Induction of DNA methylation and gene silencing by short interfering RNAs in human cells |
| 11月1日 | 張（忠明） | Hum Mol Genet. 2004 Oct 1;13(19):2233-45. Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse |
| 8日 | 竹下 | Nature AOP, published online 26 September 2004; doi:10.1038/nature02981 Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues |
| 15日 | 池田 | J Biol Chem, 278(34):31465-8, 2003. Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. |
| 22日 | 宮﨑 | Immunity. 2004 Aug;21(2):203-13. Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. |
| 29日 | 恒吉 | Cell, 119, 431-443, 2004. JunB Deficiency Leads to a Myeloproliferative Disorder Arising from Hematopoietic Stem Cells. |
| 12月6日 | 高崎 | JBC, 279, 48993-49002, 2004. Endonuclease-mediated mRNA decay requires tyrosine phosphorylation of PMR1 for the targeting and degradation of polyribosome-bound substrate mRNA. |
| 13日 | 中止 | |
| 20日 | 出原 | Science, vol.304, 1497-1500, 2004. |
| 年末年始 | 冬休み | |
| 2005年1月17日 | 岡本 | Cell 119 (2004) 87-96. Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila. |
| 24日 | 安藤 | EMBO J., 24, 209-220, 2005. A cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in nerons. |
| 31日 | 太田 | Cell, 119, 753-766, 2004. Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages. |
| 2月7日 | 田中 | PNAS vol.102 no.2 p419-424 Jan11,2005. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivo. |
| 14日 | 檜垣 | J. Nutr, 134:2623-2627,2004. Equol, a metabolite of daizein, inhibits bone loss in ovariectomized mice. |
| 21日 | 坂田 | Science Vol. 307 p739-741 2005. The Kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs. |
| 28日 | 副島 | Cells. Science 2004 306: 1568-1571. Gastric Cancer Originating from Bone Marrow－Derived. |
| 3月7日 | 金地（泰） | Blood. 2005 Feb 10. Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways. |
| 14日 | 増本 | Nature. 2005 Feb 24;433(7028):834-41. Structure of an unliganded simian immunodeficiency virus gp120 core. |
| 22日 | 城 | Genes & Dev., 18, 2074-2085, 2004. RNA length defines RNA export pathway. |
| 28日 | 休み | |
| 4月4日 | 高山 | Cell,vol.120,303-313,2005. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. |
| 11日 | 八木 | Nature genetics, 37, 31-40, 2005. Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. |
| 18日 | 吉田 | Nature Medicine11, 191 - 198, 2005. IKK-b links inflammation to obesity-induced insulin resistance. |
| 25日 | 木本 | Nature Medicine, 11, 138 - 145, 2005. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. |
| 5月9日 | 中尾 | J Biol Chem. 2005 Mar 23. in press. The oxidative stressor arsenite activates VEGF mRNA transcription by an ATF4-dependent mechanism. |
| 16日 | 矢ケ部 | Cancer cell, 2005, 7, 337-350.Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas. |
| 23日 | 福留 | Nature, 2005, 435, 58-65. Lipoprotein particles are required for Hedgehog and Wingless signalling. |
| 30日 | 金地（佐） | Nat Cell Biol. 2004 Dec;6(12):1229-35. Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. |
| 6月6日 | 中止 | |
| 13日 | 高橋 | Science, 2005, 308, 1181.Functional interaction between b-catenin and FOXO in oxidative stress signaling. |
| 20日 | 宮崎 | Nature, 2005 Jun 2;435(7042):646-51. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. |
| 27日 | 池田 | J. Biol. Chem., Feb 2005; 280: 3125 - 3128. Reduction of Cysteine Sulfinic Acid by Sulfiredoxin Is Specific to 2-Cys Peroxiredoxins. |
| 7月4日 | 常吉 | Nature, 2005, 435, 637-645. Interchromosomal associations between alternatively expressed loci. |
| 11日 | 岡本 | Cell, 2005, 121, 49-62. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. |
| 19日 | 出原 | Science, 2005, 308, 1618-1621. |
| 25日 | 高崎 | J. Biol. Chem., 2005, 280, 4289-4298. Specificity Changes in the Evolution of Type II Restriction Endonucleases A Biochemical and Bioinformatic Analysis of Restriction Enzymes that recognize unrelated Sequences. |
| 9月5日 | 王 | J.E.M. vol 202,No2, 239-248. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. |
| 12日 | 安藤 | Silveria, J. R. et al. (2005) The most infectious prion protein particles. Nature, 437, 257-261. |
| 20日 | 太田 | Nat. Immunol., Vol. 5, 730-737, 2004 The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. |
| 26日 | 檜垣 | High intensity exercise decreases global brain glucose uptake in humans. J. Physiol. in Press; published online on July 21 |
| 10月3日 | 副島 | The Transcriptional Landscape of the Mammalian Genome. Science 2005 309: 1559-1563 |
| 11日 | 金地（佐） | Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1. Nature. 2005 Jul 14;436(7048):290-3. |
| 17日 | 増本 | Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhanditis elegans. Nature, 2005, 437, 831-837. |
| 24日 | 城 | Nature 435, 839-843, 2005 MicroRNA expression profiles classify human cancers. |
| 31日 | 高山 | Nature. 2005 Mar 31;434(7033):644-8. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. |
| 11月7日 | 八木 | Suppression of Aging in Mice by the Hormone Klotho. SCIENCE 309, 1829-1833 (2005) |
| 14日 | 吉田 | Nature Immunology 6, 1123 - 1132 (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. |
| 21日 | 木本 | Nature Medicine 11, 1173 - 1179 (2005) Regulation of lung injury and repair by Toll-like receptors and hyaluronan. |
| 28日 | 中尾 | Cell. May 6, 2005: 121 (3) UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex. |
| 12月5日 | 矢ケ部 | Combretastain A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. 2005 J. Clin. Invest. 6:2992-3006 |
| 12日 | 福留 | Science 25 November 2005:
Vol. 310. no. 5752, pp. 1321 - 1324 Assistance of Microbial Glycolipid Antigen Processing by CD1e. |
| 19日 | 金地（泰） | A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nature Medicine 11:875-879.2005 |
| 2006年1月16日 | 高橋 | Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations. Nature Genetics, 37, 692-670, 2005 |
| 1月23日 | 池田 | The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science. 2005 Oct 21;310(5747):490-3 |
| 1月30日 | 宮崎 | Nat Genet. 2006 38(1):27-37. Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1. |
| 2月7日 | 塚本 | Science. 2005 Dec 2;310(5753):1510-2 Divergent immunoglobulin g subclass activity through selective Fc receptor binding. |
| 2月13日 | 岡本 | Nature 439, 31-37 Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. |
| 2月20日 | 出原 | Nat Genet, vol.37, 829-834, 2005 TACI is mutant in common variable immunodeficiency and IgA deficiency. |
| 3月6日 | 王 | Nat Med. 2006 Feb;12(2):207-13. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. |
| 3月13日 | 安藤 | Nature 439, 811-816 (2006) Histone demethylation by a family of JmjC domain-containing proteins. |
| 3月20日 | 太田 | Nature 438, 820-827 (2005) VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. |
| 3月27日 | 桧垣 | Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006, 26; 439(7075):484-9 |
| 4月3日 | 副島 | Ziyyat A, et al. CD9 controls the formation of clusters that contain tetraspanins and the integrin alpha 6 beta 1, which are involved in human and mouse gamete fusion. J Cell Sci. 2006, 119:416-24 |
| 4月10日 | 城 | Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature, March 23, 440, 561-564, 2006 |
| 4月17日 | 八木 | Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial diseas. PNAS 2005 102: 7127-7132, 2005 |
| 4月24日 | 吉田 | Intravenous apoptotic spleen cell infusion induces a TGF-b-dependent regulatory T-cell expansion. Cell Death and Differentiation (2006) 13, 41-52 |
| 5月15日 | 岡本 | KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity. Cell 125, 371-383 (April 21, 2006) |
| 5月22日 | 塚本 | Nat Cell Biol. 2006 May;8(5):516-23 APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. |
| 5月29日 | 金地（佐） | Nature. 2006 Mar 23;440(7083):556-60. RNA-mediated response to heat shock in mammalian cells. |
| 6月5日 | 高橋 | The role of receptor internalization in CD95 signaling.EMBO J. 2006 25(5):1009-23. |
| 6月12日 | 池田 | Proc Natl Acad Sci U S A. 2006 May 16;103(20):7607-7612. The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. |
| 6月19日 | 宮崎 | Nat Immunol. 7(5):507-16. (2006) T cell- and B cell-independent adaptive immunity mediated by natural killer cells. |
| 6月26日 | 矢ヶ部 | Nature 441, 898-901 (15 June 2006) CRD-BP mediates stabilization of TrCP1 and c-myc mRNA in response to -catenin signalling. |
| 7月3日 | 出原 | Nature, vol. 441, 235-238, 2006 Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. |
| 7月10日 | 高崎 | Cloning of Nt.CviQII nicking endonuclease and its cognate methyltransferase: M.CviQII methylates AG sequences. Protein Expression and Purification (in press) |
| 7月17日 | 王 | CCR6-Mediated Dendritic Cell Activation of Pathogen-Specific T Cells in Peyer's Patches. Immunity 24, 623-632, May 2006 |
| 7月24日 | 安藤 | A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature 441, 362-365 (18 May 2006) |
| 7月31日 | 太田 | Nature 442, 457-460(27 July 2006) Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN. |
| 9月4日 | 副島 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006 Aug 25;126(4):663-76. |
| 9月11日 | 松下 | Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 442, 997-1002(31 August 2006) |
| 9月19日 | 檜垣 | Beta-cell secretory dysfunction in the pathogenesis of low birth weight-associated diabetes: a murine model.Diabetes. 2005, 54(3):702-11 |
| 9月25日 | 島ノ江 | Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nature Medicine 11, 271 - 276 (2005) |
| 10月2日 | 城 | A brain-specific microRNA regulates dendritic spine development. Nature, 439, January 19, 283-289, 2006 |
| 10月10日 | 内田 | Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nature Medicine 12, 518 - 525 (2006) |
| 10月16日 | 八木 | Circadian regulator CLOCK is a histone acetyltransferase. Cell. 125(3):497-508 (2006) |
| 10月23日 | 原 | Nature. 442(7103):651-6 Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. |
| 10月30日 | 篠崎 | Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes. Science. 314(5798):126-129 (2006) |
| 11月13日 | 伊藤 | Nature Medicine - 12, 1088 - 1092 (2006) TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis. |
| 11月20日 | 岡本 | Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms. Cell 127, 199-211 (2006) |
| 11月27日 | 中尾 | Corneal avascularity is due to soluble VEGF receptor-1. Nature 443(7114) 993-997 (2006) |
| 12月4日 | 金地 | CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat Cell Biol. 2006 Sep;8(9):933-44 |
| 12月18日 | 池田 | Biochemistry. 2006 Jul 25;45(29):8959-71. Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. |